Introduction The confluence of microfluidic technology and surface plasmon resonance (SPR) sensing represents a pivotal advancement in the evolution of miniaturized analytical systems. Historically, SPR sensors—while extremely sensitive to refractive index changes at the nanoscale—have been encumbered by operational limitations. These include reliance on manual sample delivery, low multiplexing throughput, and often bulky system architecture. […]
Introduction Surface Plasmon Resonance (SPR) sensors have revolutionized label-free bio- and chemical-sensing, particularly in fields requiring ultra-sensitive detection such as medical diagnostics, food safety, and environmental monitoring. However, their development cycle is often hindered by extensive experimental iterations, high costs, and long time-to-market timelines. Predictive numerical simulations offer a strategic pathway to circumvent these challenges. […]
Introduction Surface Plasmon Resonance (SPR) sensors have emerged as powerful tools for label-free, real-time detection of biomolecular interactions. Their operational basis lies in monitoring shifts in the refractive index at a metal-dielectric interface, which correlates directly with molecular binding events occurring on the sensor’s surface. This capability has propelled SPR sensors into critical roles across […]
