Introduction Surface Plasmon Resonance Imaging (SPRi) has emerged as a vital optical sensing technique in the toolbox of modern biological research. Unlike conventional assays that depend on labeling or indirect detection, SPRi provides a label-free, real-time modality to monitor biomolecular interactions across multiple analytes simultaneously. This unique combination of high-throughput screening and non-destructive testing has […]
Introduction Surface Plasmon Resonance Imaging (SPRI) has emerged as a pivotal label-free optical technique that enables real-time observation of biomolecular interactions and cellular dynamics. Unlike conventional fluorescence-based assays, SPRI relies on monitoring changes in the refractive index at a metal-dielectric interface—typically involving gold films—making it highly sensitive to surface-bound molecular events. This unique capability allows […]
Surface Plasmon Resonance (SPR) is a powerful optical sensing technique used to detect molecular interactions in real-time without the need for labeling. A typical SPR sensor configuration often involves a metal-dielectric interface, where surface plasmons are excited under specific conditions. Glass plays a crucial role in these sensors, particularly as a substrate or a prism […]
Introduction Surface Plasmon Resonance (SPR) sensors represent a vital class of label-free biosensors that are fundamentally transforming real-time molecular detection. Relying on the interaction of light with metal surfaces to generate plasmons—coherent electron oscillations at the interface—SPR systems detect changes in the refractive index near the sensor surface, typically induced by biomolecular interactions. This optical […]
Top Applications of Surface Plasmon Resonance Sensors (SPR Sensors): SPR sensors have revolutionized the field of chemical and biological sensing by providing real-time, label-free detection of molecular interactions with exceptional sensitivity. The working principle of an SPR sensor relies on the excitation of surface plasmons—coherent oscillations of free electrons—at the interface between a metal (typically […]
