Tag: real-time biosensing

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Improving SPR Sensor Response with Wavelength and Angular Tuning Mechanisms

Predictive Accuracy of SPR Sensor Simulations
Predictive Accuracy of SPR Sensor Simulations

Introduction Surface Plasmon Resonance (SPR) sensors stand at the forefront of label-free biosensing technologies, relying on the excitation of surface plasmons—coherent electron oscillations—at metal-dielectric interfaces. The resonance condition, and hence the sensor’s response, is acutely sensitive to changes in the local refractive index, making SPR particularly valuable in the detection of biomolecules, chemicals, and environmental […]

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FEA Simulation of Label-Free Photonic Crystal Sensors

FEA Simulation of Label-Free Photonic Crystal Sensors
FEA Simulation of Label-Free Photonic Crystal Sensors

Introduction Label-Free Photonic Crystal Sensors (PhC) represent an increasingly vital class of optical biosensors, designed for real-time detection of biomolecular interactions without requiring fluorescent or radioactive labels. Unlike traditional techniques that rely on tagging molecules, PhC sensors detect shifts in light behavior as biomolecules bind near a photonic structure, offering precise, non-invasive readouts. These sensors […]