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Microfluidics SPR : Building Point-of-Care Assays That Actually Translate

Introduction The intersection of microfluidics and surface plasmon resonance (SPR) has become a pivotal frontier in the development of real-world, deployable diagnostic tools, especially for point-of-care (POC) applications. SPR, a label-free biosensing technology that detects changes in the refractive index near a sensor surface, when combined with the precision fluid control offered by microfluidics, opens […]

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SPR vs LSPR vs SPRi: Which Plasmonic Platform Fits Your First Experiment?

Introduction Surface plasmon-based sensing platforms have become indispensable tools in biosensing, pharmaceutical development, and environmental diagnostics. Among these, Surface Plasmon Resonance (SPR), Localized Surface Plasmon Resonance (LSPR), and Surface Plasmon Resonance Imaging (SPRi) represent the most widely applied technologies in the field of plasmonics. Each approach has distinct physical principles, detection strategies, and performance parameters […]

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Numerical Modeling of SPR Sensors

Introduction Surface Plasmon Resonance (SPR) sensors have emerged as powerful tools for label-free, real-time detection of biomolecular interactions. Their operational basis lies in monitoring shifts in the refractive index at a metal-dielectric interface, which correlates directly with molecular binding events occurring on the sensor’s surface. This capability has propelled SPR sensors into critical roles across […]