Introduction Surface plasmon resonance (SPR) has emerged as a pivotal technique in the detection and analysis of biomolecular interactions, enabling highly sensitive label-free sensing based on optical phenomena at metal-dielectric interfaces. The resonance condition, where incident light couples with surface plasmons on metallic films, leads to a characteristic drop in reflected intensity, which is exquisitely […]
Introduction Surface Plasmon Resonance (SPR) sensors have long stood as a cornerstone of label-free biosensing technology, particularly due to their ability to detect molecular interactions with high specificity by measuring changes in the local refractive index. The essential operational principle behind SPR involves the excitation of surface plasmons—coherent delocalized electron oscillations—at the interface between a […]
